Does Intravenous Vitamin C Work for COVID-19?

Doctors are using intravenous vitamin C to treat COVID-19 patients in China and Italy, where clinical trials are being conducted. Doctors in some areas of the U.S. are using it. Although it isn’t standard protocol in hospitals here, you can usually find it in private holistic clinics as an adjunct to other therapies and as an overall health booster.

But if you or a loved one happens to end up in the hospital with COVID-19, based on the few studies that have been documented, I would try my best to get it prescribed ASAP. If you are not able to find a treatment center for IV vitamin C, or are afraid of needles, here is Dr. Magaziner’s COVID-19 wellness recommendations to strengthen your immunity and resistance to the coronavirus: https://drmagaziner.com/news/dr-magaziners-coronavirus-covid-19-wellness-recommendations/

What is IV vitamin C?

A solution of vitamin C is administered intravenously in the arm so that the vitamin C goes directly into the bloodstream. When you take vitamin C supplements, it goes into the stomach and intestines. If the dose is higher than your body needs, you excrete it through urine. No matter how much vitamin C you take via a supplement you will not be able to achieve the blood levels you’d get from intravenous vitamin C.

How does it work?

It’s counter-intuitive, but even though vitamin C is an antioxidant when it is infused into your blood in very high doses it creates free radicals that destroy viruses and bacterial. At the same time, IV vitamin C strengthens the body’s antioxidant protection, which is especially important during an illness because serious infections use up the body’s antioxidants and vitamin very quickly.

Is it safe?

Yes, but it must be administered by a medical professional and few hospitals in the U.S. are prescribing it for COVID-19, so you have to beg for it. It is administered in private clinics as a preventative treatment against COVID-19 and for other illnesses including cancer. https://www.cancer.gov/about-cancer/treatment/cam/hp/vitamin-c-pdq

Intravenous vitamin C keeps people healthier longer.

Covid19 pneumonia is an extremely rapidly developing disease with a high mortality rate. The main pathogenesis is the acute lung injury that causes Acute Respiratory Distress Syndrome (ARDS) and death. Clinical studies and reports demonstrate that a timely administration of high dose IV Vit-C improves the outcome of Covid19 infection.

Since the development of vaccines or antiviral drugs may take a long time to develop, the use of IV Vit-C as a universal agent for ARDS may have benefits for Covid19 and other viral diseases.

Where has IV Vit-C been used successfully?

Recently, it was used in China to treat COVID-19 patients. Data published by the “Expert Group on clinical Treatment of New Corona Virus Disease in Shanghai” (Shanghai, 2019) discusses the use of IV Vit-C as a safe and effective treatment for hospitalized COVID-19 patients. The Chinese facility had 358 COVID -19 patients on March 17th, 2020. Fifty patients with moderate to severe infection were treated with the vitamin C infusion. None of the patients died and all of them improved. Their length of stay at the hospital was 3 to 5 days shorter than the typical 30-day hospital stay of the patients who did not receive the Vitamin-C IV.

Intravenous vitamin-C therapy has a safe track record and is relatively inexpensive. It shortens hospital stays, making it cost effective, and it frees up hospital beds and resources.

A 2020 meta-analysis of 9 existing clinical trials compared a group of people who received an IV infusion with a group of controls. The researchers found that, on average, IV vitamin C shortened the length of mechanical ventilation by 14%. The effect varied from study to study, though, and it was greater when members of the control group needed longer periods of ventilation.

A 2019 meta-analysis found that vitamin C infusions could shorten the length of intensive care unit stays by 7.8% and the need for mechanical ventilation by 18.2%. The study looked at a wide range of medical conditions, but not at COVID-19.

2019 randomized controlled trial looked at people with sepsis and severe acute respiratory failure, which are two complications that people with severe COVID-19 may experience. Participants received either a placebo or a vitamin C infusion. Although vitamin C did not decrease the rate of organ failure or sepsis, fewer people in the vitamin C group died.

What can you do now?

It might be awhile until a safe vaccine against COVID-19 is available. In the meantime, support your immune system with the recommended supplements and eat the color of the rainbow, including lots of fresh berries and vegetables, low-fat healthy protein, legumes, and nuts, and healthy fats (olive and avocado oils).

References

Alberto Boretti, Bimal Krishna Banik. Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome. PharmaNutrition. 2020 Jun; 12: 100190.

Paul S. Anderson. Intravenous ascorbic acid for supportive treatment in hospitalized COVID-19 patients. 12 March 2020. International Society for Orthomolecular Medicine.

Barbra Cohn cared for her husband Morris for 10 years. He passed away from younger-onset Alzheimer’s disease in 2010. Afterward, she was compelled to write “Calmer Waters: The Caregiver’s Journey Through Alzheimer’s & Dementia”—Winner of the 2018 Book Excellence Award in Self-Help—in order to help other caregivers feel healthier and happier, have more energy, sleep better, feel more confident, deal with feelings of guilt and grief, and to ultimately experience inner peace. “Calmer Waters” is available at AmazonBarnes & NobleBoulder Book StoreTattered Cover Book Store,  Indie Bound.org, and many other fine independent bookstores, as well as public libraries.

The most important supplements you need for protection against COVID-19 and influenza

 

We’re already getting warnings from the CDC and other prominent doctors and scientists that COVID-19 is not going away. Coupled with the influenza threat, which normally starts around October and lasts through March or April, it’s a good idea to start building up your immune system now.

Here are the vital nutritional supplements that health practitioners recommend to protect you from COVID-19 and influenza.

Vitamin D
All the recently published studies are showing that individuals with low levels of vitamin D fared worse from COVID-19 than those with higher levels. Additionally, in a study published April 2020 there is evidence that vitamin D3 supplementation might reduce your risk of influenza and COVID-19 infections and deaths.

The authors of one study recommended that people at risk of influenza and /or COVID-19 consider taking 10,000 IU a day of vitamin D3 for a few weeks to rapidly raise their vitamin D concentrations, followed by 5000 IU a day. For treatment of people who become infected with COVID-19, higher vitamin D3 doses might be useful. https://pubmed.ncbi.nlm.nih.gov/32252338/

Another study advises that older adults, especially those with Parkinson’s disease, should take 2000-5000 IU a day of vitamin D3 which has the potential to slow Parkinson’s while also potentially offering protection against OVID-19. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287983/

How does vitamin D help?

Vitamin D supports immunity in two ways: 1) It is necessary for the production of antiviral peptides in the respiratory tract, making the respiratory tract less likely to be infected with a virus. 2) It helps promote a balanced inflammatory immune response.

Researchers at Northwestern University analyzed publicly available patient data from 10 countries and discovered a strong correlation between vitamin D levels and cytokine storm—a hyper-inflammatory condition caused by an overactive immune system — as well as a correlation between vitamin D deficiency and mortality. http://www.sciencedaily.com/releases/2020/05/200507121353.htm

According to Ali Daneshkhah, the study’s first author, “Cytokine storm can severely damage lungs and lead to acute respiratory distress syndrome and death in patients. This is what seems to kill a majority of COVID-19 patients, not the destruction of the lungs by the virus itself. It is the complications from the misdirected fire from the immune system.”

The research team believes that this is where vitamin D plays a major role. Vitamin D enhances our innate immune systems, and prevents our immune systems from becoming dangerously overactive. This means that having healthy levels of vitamin D could protect patients against severe complications, including death from COVID-19.

Lead researcher Vadim Backman said, “ Our analysis shows that it might be as high as cutting the mortality rate in half. It will not prevent a patient from contracting the virus, but it may reduce complications and prevent death in those who are infected.

Getting enough Vitamin D

Vitamin D is made in the skin as a result of exposure to sunlight. The problem is, most of us do not get the sunlight needed for cutaneous vitamin D synthesis.

Vitamin D is actually a hormone that is made in the skin as a result of exposure to sunlight. The problem is, if you live at a latitude of 42 degrees (a line approximately between the northern border of California and Boston) the sun’s rays are too low between November and February for your skin to get the sunlight needed for cutaneous vitamin D synthesis.

If you live at a latitude below 34 degrees north (a line between Lost Angeles and Columbia, South Carolina) your body can make vitamin D from sun exposure yearlong. However, it’s important to expose a large portion of bare skin (like your midriff) to mid-day sun for at least 15 minutes every day. Most people are unable to fit this into their schedule, so vitamin D supplementation is highly recommended, especially since so few foods contain it.

According to Michael Holick, PhD, MD, an internationally recognized expert on vitamin D and director of the Vitamin D, Skin and Bone Research Laboratory at Boston University Medical Center, approximately one billion people throughout the world are deficient in vitamin D.

Blacks, Browns, and other dark skinned individuals are at even higher risk for inadequate levels of vitamin D because their skin isn’t able to absorb as much sunlight. This may be one of the reasons that these populations have fared so poorly in the fight against COVID-19.

Foods that are high in vitamin D

  • Cod liver oil, salmon, tuna, sardines, herring, smoked whitefish, rainbow trout, swordfish
  • Milk and fortified non-dairy drinks (orange juice, coconut, soy, almond, etc.)
  • Fortified cereals
  • Mushrooms are the only food in the produce section that has vitamin D. Portobello, maitake, white button have the highest vitamin D content.

How much should you take?

Dr. Holick says, “I recommend to all of my patients that they should take 2000-3000 IU of vitamin D a day from dietary sources, sensible sun exposure and supplements. I believe that it is important for women to take at least 2000 IU of vitamin D a day. Although many of the studies are association studies there continues to be strong evidence that increasing vitamin D intake has other health benefits besides those for bone health. From my perspective there is no downside to increasing your vitamin D intake to levels I have recommended in “The Vitamin D Solution” which is 1000 IU of vitamin D a day for children and 2000-3000 IU of vitamin D for adults.” https://www.nejm.org/doi/full/10.1056/nejmra070553

If you’re over 60, consider taking at least 3,000 IU daily during the summer, and take 5,000 IU in the winter if you want to increase your protection against COVIC-19 and other respiratory illnesses.

Zinc

Zinc is naturally found in the body and is the second most abundant trace element. It is commonly taken to relieve symptoms of the common cold and influenza. It prevents viral replication and the binding of viruses to cells. However, moderate deficiencies can increase the risk of infection.

How does it help?

Researchers are working on lab studies showing how zinc supplementation can help reduce risk of COVID-19. But we know this: Zinc is thoroughly involved in cell-mediated immunity against any infectious agent such as bacteria and virus. Zinc is one of the major factors that control function and proliferation of neutrophils, natural killer (NK) cells, macrophages, and T and B lymphocytes as well as cytokine production by the immune cells. Zinc also mediates protection from the adverse effect of ROS that are generally produced during inflammatory processes. 

Zinc supplementation might play an important role to COVID-19 patients by adding immune boosting effects with anti-viral drugs.

Foods that are high in zinc

  • Meat
  • Shellfish
  • Legumes—chickpeas, lentils, beans
  • Seeds—pumpkin
  • Nuts —cashews,almonds, pinenuts, peanuts
  • Dairy
  • Eggs

How much should you take?

The recommended daily allowance of zinc will vary according to the age, sex, and health conditions of an individual. For healthy adults, the recommended daily allowance is typically 15–30 mg of elemental zinc. Make sure the supplement contains some copper, which makes the zinc more absorbable. The supplement should contain a ratio of 15 mg of zinc to 1 mg of copper.

Other important supplements

Vitamin C and selenium are antioxidants with lots of studies showing how they help support the immune system.

Selenium

Selenium is an essential trace element obtained from the diet (i.e. fish, meat and cereals) which has been found to affect the severity of a number of viral diseases in animals and humans.

Margaret Rayman, Professor of Nutritional Medicine at the University of Surrey, said: “Given the history of viral infections associated with selenium deficiency, we wondered whether the appearance of COVID-19 in China could possibly be linked to the belt of selenium deficiency that runs from the north-east to the south-west of the country.”

Examining data from provinces and municipalities with more than 200 cases and cities with more than 40 cases, researchers found that areas with high levels of selenium were more likely to recover from the virus. For example, in the city of Enshi in Hubei Province, which has the highest selenium intake in China, the cure rate (percentage of COVID-19 patients declared ‘cured’) was almost three-times higher than the average for all the other cities in Hubei Province. By contrast, in Heilongjiang Province, where selenium intake is among the lowest in the world, the death rate from COVID-19 was almost five-times as high as the average of all the other provinces outside of Hubei.

Most convincingly, the researchers found that the COVID-19 cure rate was significantly associated with selenium status, as measured by the amount of selenium in hair, in 17 cities outside of Hubei. http://www.sciencedaily.com/releases/2020/04/200429105907.htm

How does it help?

Selenium supplementation modulates the inflammatory response in acute respiratory distress syndrome (ARDS) patients by restoring the antioxidant capacity of the lungs, thus improving lung function. When there isn’t enough antioxidant capacity in the lungs because of selenium deficiency, mutations within viruses occur. This makes them even more dangerous and infectious.

Foods that are high in selenium

  • Brazil nuts
  • Tuna
  • Shellfish–oysters
  • Pork chops
  • Beef
  • Chicken
  • Firm Tofu
  • Whole wheat pasta, kamut, oatmeal, brown rice
  • Shrimp
  • Shitake mushrooms

How much should you take?

It’s best to make sure you’re eating foods containing selenium. When taken by mouth: Selenium is LIKELY SAFE for most people when taken by mouth in doses less than 400 mcg daily, short-term. However, selenium is POSSIBLY UNSAFE when taken by mouth in high doses or for a long time. Taking doses above 400 mcg can increase the risk of developing selenium toxicity. Most multi-vitamins contain selenium. Check yours (and yes, you shuld be taking a multi-vitamin. Make sure it contains adequate selenium. The recommended Daily Value (DV) or daily allowance for selenium is 55 mcg per day for adults. During pregnancy, a woman should get 60 mcg, and lactating women should get 70 mcg a day.

Look for my next blog in which I’ll discuss how vitamin C infusions can help keep you from being put on a ventilator if you get COVID-19.


 

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Barbra Cohn cared for her husband Morris for 10 years. He passed away from younger-onset Alzheimer’s disease in 2010. Afterward, she was compelled to write “Calmer Waters: The Caregiver’s Journey Through Alzheimer’s & Dementia”—Winner of the 2018 Book Excellence Award in Self-Help—in order to help other caregivers feel healthier and happier, have more energy, sleep better, feel more confident, deal with feelings of guilt and grief, and to ultimately experience inner peace. “Calmer Waters” is available at AmazonBarnes & NobleBoulder Book StoreTattered Cover Book Store,  Indie Bound.org, and many other fine independent bookstores, as well as public libraries.