Monthly Archives: August 2020

Why it’s important to get an early diagnosis when cognitive problems appear

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Doctor talking with patient

There were several indications that something was wrong with my husband two years before he was diagnosed. This tall, good-looking man, a graduate of the Wharton School of Business at the University of Pennsylvania, was having trouble calculating how much tip to leave a waitress. When we went to Spain for our twenty-fifth anniversary, Morris couldn’t figure out how much money the hotel would cost in dollars. This man, who once memorized trains and airplane schedules without even trying, followed me around the city like a puppy dog as we boarded a subway or bus enroute to tourist attractions.

That following fall — our daughter’s last year in high school — Morris couldn’t give directions to a friend who was taking the SAT at the high school my husband had attended. I got out the map to help him, but he couldn’t read the map. That was the moment I knew something was very wrong. When he left for a road trip to California without our son and forgot his suitcase, I sat on the stairs and cried. I couldn’t deny it any longer. I had a strong suspicion that Morris had Alzheimer’s disease, and although I pleaded with him for two years to see a neurologist, he refused.

What if he had gotten an early diagnosis? Would it have helped?

There’s no way to know for sure, but probably it would have. Because as soon as he started taking Aricept he stopped getting lost driving around our small city. And I started giving him nutritional supplements, which also seemed to help. Read “5 Things that Help Dementia that your Doctor Probably Hasn’t Mentioned.” https://barbracohn.com/2019/09/25/5-things-that-help-dementia-that-your-doctor-probably-hasnt-mentioned/

Professionals, both researchers and physicians and the Alzheimer’s Association, recommend that an early, accurate diagnosis is the key to living a less stressful life for both the patient and the family.

Here’s why:

  1. Cognitive problems can be caused by a number of physical conditions other than Alzheimer’s disease, vascular cognitive impairment, Lewy Bodies dementia and Frontotemporal dementia (FTD). These include thyroid problems, hydrocephalus, a brain tumor, and even depression. When my mother was severely dehydrated and hospitalized with a urinary tract infection (UTI), a psychiatrist called to tell me that she had full-blown dementia. “No she doesn’t,” I said. And sure enough, after being put on an IV saline drip Mom regained her full mental capacity. Memory problems can result from dehydration, severe diabetes and some forms of Parkinson’s disease, traumatic brain injury, HIV, and Huntington’s disease.

Certain medications can affect mental clarity and balance. Be sure to ask your pharmacist about drug contraindications, and interactions with natural supplements. Alcohol abuse and binge drinking can destroy brain cells that are critical for memory, thinking, and decision making and mimic or lead to dementia.

2. Cognitive symptoms may be reversible. There are a number of holistic doctors who claim that their protocol can treat the root cause of cognitive decline and Alzheimer’s disease. Please read my blog ” Significant study points to MIND diet for improving brain health and preventing Alzheimer’s disease.” https://barbracohn.com/2018/11/09/significant-study-points-to-mind-diet-for-improving-brain-health-and-preventing-alzheimers-disease/

Dale Bredesen, MD, a physician scientist in the Department of Pharmacology at UCLA who’s published more than 220 papers on Alzheimer’s, has spent 30 years looking at the root causes of the neurodegenerative phenomenon in hopes of eradicating it. In 2018, Bredesen published the case studies of more than 100 patients in cognitive decline in the Journal of Alzheimer’s Disease & Parkinsonism. https://www.omicsonline.org/open-access/reversal-of-cognitive-decline-100-patients-2161-0460-1000450.pdf

In her editorial in the Lancet Neurology, published in May 2020, Joanna Hellmuth, MD, of the UCSF Memory and Aging Center, said the “Bredesen protocol” – named by neurologist Dale Bredesen, MD – has reeled in patients and their families seeking hope outside of the physician’s office for a disease that is currently incurable.

The Bredesen protocol is propounded in his 2017 bestseller The End of Alzheimer’s Program and can be accessed for $1,399, which includes protocol assessments, lab tests and contact with practitioners, who provide the regimen for additional fees. Online support and cognitive games are available for an additional monthly charge. This protocol is timely, costly and requires steadfastness. But if you have the time and means, it’s probably worth a try.

3. An early diagnosis is empowering. Before the disease has progressed to the point where decision making is difficult, the patient can be included in financial and estate planning, creating end-of-life wishes and durable power of attorney decisions, etc.

4. An early diagnosis is easier for the physician to make when the patient is able to answer questions. Later in the progression of the disease, the patient isn’t able to make observations or answer accurately.

5. Family and loved ones who might be confused by particular behaviors such as anger, depression, disinterest, can better understand why their parent or spouse or significant other is behaving the way they are. This helps to preserve the person’s dignity rather than have someone close to them yell at them, treat them poorly, or want to distance them self, etc.

6. Individuals diagnosed early can take advantage of support groups, and caregivers can learn ways to better manage medications, and learn strategies for coping with unexpected and unusual behaviors and the ordinary progression of the disease. The Alzheimer’s Association was a godsend for me. I was able to connect with other caregivers who knew exactly what I was going through. I could talk about what was happening all day with my best friend, but there was no way she would be able to fully understand the stress of caregiving and the grief of losing a partner to Alzheimer’s. https://www.alz.org/alzheimers-dementia/research_progress/clinical-trials/about-clinical-trials

7. Getting an early diagnosis provides the opportunity to possibly enroll in a clinical trial. TrialMatch is a clinical trial matching service for Alzheimer’s and other dementias. It is a free, easy-to-use service that connects individuals living with AD, caregivers, and healthy volunteers with current research studies. Their continuously updated database of AD clinical studies includes hundreds of pharmacological and non-pharmacological studies being conducted at sites throughout the U.S. and online.

8. An early diagnosis allows the patient to prioritize what is important to them, whether it’s creating a masterpiece or traveling the world. There is still time at this point in the disease to enjoy a happy, satisfying life.

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Barbra Cohn cared for her husband Morris for 10 years. He passed away from younger-onset Alzheimer’s disease in 2010. Afterward, she was compelled to write “Calmer Waters: The Caregiver’s Journey Through Alzheimer’s & Dementia”—Winner of the 2018 Book Excellence Award in Self-Help—in order to help other caregivers feel healthier and happier, have more energy, sleep better, feel more confident, deal with feelings of guilt and grief, and to ultimately experience inner peace. “Calmer Waters” is available at Amazon, Barnes & Noble, Boulder Book Store, Tattered Cover Book Store,  Indie Bound.org, and many other fine independent bookstores, as well as public libraries.

Does Intravenous Vitamin C Work for COVID-19?

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Doctors are using intravenous vitamin C to treat COVID-19 patients in China and Italy, where clinical trials are being conducted. Doctors in some areas of the U.S. are using it. Although it isn’t standard protocol in hospitals here, you can usually find it in private holistic clinics as an adjunct to other therapies and as an overall health booster.

But if you or a loved one happens to end up in the hospital with COVID-19, based on the few studies that have been documented, I would try my best to get it prescribed ASAP. If you are not able to find a treatment center for IV vitamin C, or are afraid of needles, here is Dr. Magaziner’s COVID-19 wellness recommendations to strengthen your immunity and resistance to the coronavirus: https://drmagaziner.com/news/dr-magaziners-coronavirus-covid-19-wellness-recommendations/

What is IV vitamin C?

A solution of vitamin C is administered intravenously in the arm so that the vitamin C goes directly into the bloodstream. When you take vitamin C supplements, it goes into the stomach and intestines. If the dose is higher than your body needs, you excrete it through urine. No matter how much vitamin C you take via a supplement you will not be able to achieve the blood levels you’d get from intravenous vitamin C.

How does it work?

It’s counter-intuitive, but even though vitamin C is an antioxidant when it is infused into your blood in very high doses it creates free radicals that destroy viruses and bacterial. At the same time, IV vitamin C strengthens the body’s antioxidant protection, which is especially important during an illness because serious infections use up the body’s antioxidants and vitamin very quickly.

Is it safe?

Yes, but it must be administered by a medical professional and few hospitals in the U.S. are prescribing it for COVID-19, so you have to beg for it. It is administered in private clinics as a preventative treatment against COVID-19 and for other illnesses including cancer. https://www.cancer.gov/about-cancer/treatment/cam/hp/vitamin-c-pdq

Intravenous vitamin C keeps people healthier longer.

Covid19 pneumonia is an extremely rapidly developing disease with a high mortality rate. The main pathogenesis is the acute lung injury that causes Acute Respiratory Distress Syndrome (ARDS) and death. Clinical studies and reports demonstrate that a timely administration of high dose IV Vit-C improves the outcome of Covid19 infection.

Since the development of vaccines or antiviral drugs may take a long time to develop, the use of IV Vit-C as a universal agent for ARDS may have benefits for Covid19 and other viral diseases.

Where has IV Vit-C been used successfully?

Recently, it was used in China to treat COVID-19 patients. Data published by the “Expert Group on clinical Treatment of New Corona Virus Disease in Shanghai” (Shanghai, 2019) discusses the use of IV Vit-C as a safe and effective treatment for hospitalized COVID-19 patients. The Chinese facility had 358 COVID -19 patients on March 17th, 2020. Fifty patients with moderate to severe infection were treated with the vitamin C infusion. None of the patients died and all of them improved. Their length of stay at the hospital was 3 to 5 days shorter than the typical 30-day hospital stay of the patients who did not receive the Vitamin-C IV.

Intravenous vitamin-C therapy has a safe track record and is relatively inexpensive. It shortens hospital stays, making it cost effective, and it frees up hospital beds and resources.

A 2020 meta-analysis of 9 existing clinical trials compared a group of people who received an IV infusion with a group of controls. The researchers found that, on average, IV vitamin C shortened the length of mechanical ventilation by 14%. The effect varied from study to study, though, and it was greater when members of the control group needed longer periods of ventilation.

A 2019 meta-analysis found that vitamin C infusions could shorten the length of intensive care unit stays by 7.8% and the need for mechanical ventilation by 18.2%. The study looked at a wide range of medical conditions, but not at COVID-19.

A 2019 randomized controlled trial looked at people with sepsis and severe acute respiratory failure, which are two complications that people with severe COVID-19 may experience. Participants received either a placebo or a vitamin C infusion. Although vitamin C did not decrease the rate of organ failure or sepsis, fewer people in the vitamin C group died.

What can you do now?

It might be awhile until a safe vaccine against COVID-19 is available. In the meantime, support your immune system with the recommended supplements and eat the color of the rainbow, including lots of fresh berries and vegetables, low-fat healthy protein, legumes, and nuts, and healthy fats (olive and avocado oils).

References

Alberto Boretti, Bimal Krishna Banik. Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome. PharmaNutrition. 2020 Jun; 12: 100190.

Paul S. Anderson. Intravenous ascorbic acid for supportive treatment in hospitalized COVID-19 patients. 12 March 2020. International Society for Orthomolecular Medicine.

Barbra Cohn cared for her husband Morris for 10 years. He passed away from younger-onset Alzheimer’s disease in 2010. Afterward, she was compelled to write “Calmer Waters: The Caregiver’s Journey Through Alzheimer’s & Dementia”—Winner of the 2018 Book Excellence Award in Self-Help—in order to help other caregivers feel healthier and happier, have more energy, sleep better, feel more confident, deal with feelings of guilt and grief, and to ultimately experience inner peace. “Calmer Waters” is available at Amazon, Barnes & Noble, Boulder Book Store, Tattered Cover Book Store,  Indie Bound.org, and many other fine independent bookstores, as well as public libraries.