Can you prevent COVID-19 with supplements or medications?

Man fighting viruses and bacteria

The short answer is not really. But there’s a lot you can do to boost your immune system.

You’ve probably heard about the use of ivermectin, the anti-parasite drug that people are using to prevent COVID. Clinical trials have repeatedly failed to demonstrate the drug is effective against the virus. Yet, many continue to ignore the warning that taking ivermectin can cause harmful side effects and even death.

The confusion arose initially because the use of ivermectin in India was showing some promising results. Shortly after, however, the group that was recommending it updated their guidance. Their original message was that ivermectin shortened and lessened symptoms based on the information from a European panel. Their new guidance recommends “against using ivermectin for treatment of patients with any severity of COVID-19. Ivermectin should only be used in the context of a randomized controlled trial.”

Epidemiological data from other countries that recommended ivermectin suggests that ivermectin didn’t slow down the rate of new infection. As of May 2021, there isn’t reliable clinical evidence indicating that ivermectin is beneficial in preventing or curing COVID-19. The WHO and the U.S. FDA have adopted a similar position stating that “ivermectin should not be used for the treatment of outpatients with COVID-19, unless in the context of a clinical trial.”

Remdesivir is the only drug that is approved by the FDA to treat COVID-19. It is NOT used to prevent it.

No supplements have been clinically proven to reduce the risk of contracting COVID-19. However, it doesn’t hurt, and it may very well help, to boost your immune system in the same way you would in order to stave off colds and flu.

Vitamins and minerals that support your immunity

Vitamin A

Beta Carotene is the antioxidant of choice for people who are unsure about which vitamin A to take. It is the precursor of vitamin A and can be converted into vitamin A if the body needs it. It gives added protection to the immune system, skin, eyes, and lungs.

Vitamin B complex

B vitamins are important for a healthy immune response, and numerous healthy body processes.

Vitamin C

Vitamin C (as ascorbic acid, calcium ascorbate) is the body’s primary water-soluble antioxidant, which makes it an important weapon in your immune system’s arsenal against bacteria and viruses. It also helps protect unsaturated fatty acids, and the fat-soluble vitamins A and E from being oxidized, therefore protecting their potency.  Since your body can’t manufacture it, vitamin C must be obtained through diet and supplementation. A protective vitamin essential to over-all body health, vitamin C also helps:  in the production of collagen and maintenance of healthy skin; promote the healing of wounds, scar tissue, fractures;  give strength to blood vessels; prevent and treat the common cold; the body utilize iron and folic acid; support the thymus gland; enhance T-cell production, increasing resistance to viral and bacterial infections, and some allergies.

Vitamin D

Vitamin D supports immunity in two ways: 1) It is necessary for the production of antiviral peptides in the respiratory tract, making the respiratory tract less likely to be infected with a virus. 2) It helps promote a balanced inflammatory immune response.

Researchers at Northwestern University analyzed publicly available patient data from 10 countries and discovered a strong correlation between vitamin D levels and cytokine storm—a hyper-inflammatory condition caused by an overactive immune system — as well as a correlation between vitamin D deficiency and mortality. http://www.sciencedaily.com/releases/2020/05/200507121353.htm

According to Ali Daneshkhah, the study’s first author, “Cytokine storm can severely damage lungs and lead to acute respiratory distress syndrome and death in patients. This is what seems to kill a majority of COVID-19 patients, not the destruction of the lungs by the virus itself. It is the complications from the misdirected fire from the immune system.”

The research team believes that this is where vitamin D plays a major role. Vitamin D enhances our innate immune systems, and prevents our immune systems from becoming dangerously overactive. This means that having healthy levels of vitamin D could protect patients against severe complications, including death from COVID-19.

Lead researcher Vadim Backman said, “ Our analysis shows that it might be as high as cutting the mortality rate in half. It will not prevent a patient from contracting the virus, but it may reduce complications and prevent death in those who are infected.

Selenium

Selenium is an essential trace element obtained from the diet (i.e. fish, meat and cereals) which has been found to affect the severity of a number of viral diseases in animals and humans.

Margaret Rayman, Professor of Nutritional Medicine at the University of Surrey, said: “Given the history of viral infections associated with selenium deficiency, we wondered whether the appearance of COVID-19 in China could possibly be linked to the belt of selenium deficiency that runs from the north-east to the south-west of the country.”

Examining data from provinces and municipalities with more than 200 cases and cities with more than 40 cases, researchers found that areas with high levels of selenium were more likely to recover from the virus. For example, in the city of Enshi in Hubei Province, which has the highest selenium intake in China, the cure rate (percentage of COVID-19 patients declared ‘cured’) was almost three-times higher than the average for all the other cities in Hubei Province. By contrast, in Heilongjiang Province, where selenium intake is among the lowest in the world, the death rate from COVID-19 was almost five-times as high as the average of all the other provinces outside of Hubei.

Most convincingly, the researchers found that the COVID-19 cure rate was significantly associated with selenium status, as measured by the amount of selenium in hair, in 17 cities outside of Hubei. http://www.sciencedaily.com/releases/2020/04/200429105907.htm

Zinc

You may have used zinc lozenges to shorten the length of a cold. It does seem to work. Zinc has been shown to inhibit various coronaviruses in a couple of studies. SARS coronavirus, and ZN (2+) inhibits coronavirus.  However, it hasn’t been tested on COVID-19. Still, it is always a good idea to make sure you are taking a zinc supplement, and that doesn’t mean the zinc lozenge. Most people are deficient in zinc. A researcher at the University of Pittsburgh recommends taking 25 mg of zinc morning and evening.

Herbs and mushrooms

Echinacea

Echinacea is one of America’s best-selling herbs for fighting colds and upper respiratory illnesses and stimulating the immune system to help fight infections for good reason. It supports the immune system by activating white blood cells, promotes nonspecific T-cell activation, a type of white blood cell that’s important in providing resistance to bacteria and viruses, and it activates a non-specific immune response via a part of the immune system known as the alternate complement pathway.

Astragalus membranaceus (root extract) – also known as huang qi, was used in China for at least 2,000 years before European botanists discovered its medicinal qualities in the 1700s.  In China this popular herb is believed to strengthen chi, the body’s defensive energy that protects against invading pathogens such as bacteria and viruses. Western herbalists classify astragalus as an adaptogenic herb, meaning that it is a substance that normalizes and balances all of the body’s systems, increasing your ability to handle physical and mental stress.

Ganoderma lucidum (fruit extract) – also known as Ling zhi and Rieshi, this mushroom has been highly esteemed in Chinese medicine for more than 4,000  years for its ability to promote longevity and maintain vitality. There have been numerous studies in the past two decades done on the mushroom, and scientists have discovered that it contains anti-inflammatory agents and other compounds including polysaccharides, amino acids, triterpines, ascorbic acid, sterols, lipids, alkaloids, and trace minerals, that are being studied for their effect on the immune system.

Stay healthy by maintaining a healthy lifestyle

These are just some of the immune-boosting and stimulating natural ingredients that can help you stay strong and resistant to the flu and colds. Even more important is getting enough sleep, eating plenty of fruits, vegetables, and low-fat protein, and exercising regularly.

All the best to you and your family for a healthy, beautiful fall.

Barbra Cohn cared for her husband Morris for 10 years. He passed away from younger-onset Alzheimer’s disease in 2010. Afterward, she was compelled to write “Calmer Waters: The Caregiver’s Journey Through Alzheimer’s & Dementia”—Winner of the 2018 Book Excellence Award in Self-Help—in order to help other caregivers feel healthier and happier, have more energy, sleep better, feel more confident, deal with feelings of guilt and grief, and to ultimately experience inner peace. “Calmer Waters” is available at AmazonBarnes & NobleBoulder Book StoreTattered Cover Book Store,  Indie Bound.org, and many other fine independent bookstores, as well as public libraries.

The most important supplements you need for protection against COVID-19 and influenza

 

We’re already getting warnings from the CDC and other prominent doctors and scientists that COVID-19 is not going away. Coupled with the influenza threat, which normally starts around October and lasts through March or April, it’s a good idea to start building up your immune system now.

Here are the vital nutritional supplements that health practitioners recommend to protect you from COVID-19 and influenza.

Vitamin D
All the recently published studies are showing that individuals with low levels of vitamin D fared worse from COVID-19 than those with higher levels. Additionally, in a study published April 2020 there is evidence that vitamin D3 supplementation might reduce your risk of influenza and COVID-19 infections and deaths.

The authors of one study recommended that people at risk of influenza and /or COVID-19 consider taking 10,000 IU a day of vitamin D3 for a few weeks to rapidly raise their vitamin D concentrations, followed by 5000 IU a day. For treatment of people who become infected with COVID-19, higher vitamin D3 doses might be useful. https://pubmed.ncbi.nlm.nih.gov/32252338/

Another study advises that older adults, especially those with Parkinson’s disease, should take 2000-5000 IU a day of vitamin D3 which has the potential to slow Parkinson’s while also potentially offering protection against OVID-19. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287983/

How does vitamin D help?

Vitamin D supports immunity in two ways: 1) It is necessary for the production of antiviral peptides in the respiratory tract, making the respiratory tract less likely to be infected with a virus. 2) It helps promote a balanced inflammatory immune response.

Researchers at Northwestern University analyzed publicly available patient data from 10 countries and discovered a strong correlation between vitamin D levels and cytokine storm—a hyper-inflammatory condition caused by an overactive immune system — as well as a correlation between vitamin D deficiency and mortality. http://www.sciencedaily.com/releases/2020/05/200507121353.htm

According to Ali Daneshkhah, the study’s first author, “Cytokine storm can severely damage lungs and lead to acute respiratory distress syndrome and death in patients. This is what seems to kill a majority of COVID-19 patients, not the destruction of the lungs by the virus itself. It is the complications from the misdirected fire from the immune system.”

The research team believes that this is where vitamin D plays a major role. Vitamin D enhances our innate immune systems, and prevents our immune systems from becoming dangerously overactive. This means that having healthy levels of vitamin D could protect patients against severe complications, including death from COVID-19.

Lead researcher Vadim Backman said, “ Our analysis shows that it might be as high as cutting the mortality rate in half. It will not prevent a patient from contracting the virus, but it may reduce complications and prevent death in those who are infected.

Getting enough Vitamin D

Vitamin D is made in the skin as a result of exposure to sunlight. The problem is, most of us do not get the sunlight needed for cutaneous vitamin D synthesis.

Vitamin D is actually a hormone that is made in the skin as a result of exposure to sunlight. The problem is, if you live at a latitude of 42 degrees (a line approximately between the northern border of California and Boston) the sun’s rays are too low between November and February for your skin to get the sunlight needed for cutaneous vitamin D synthesis.

If you live at a latitude below 34 degrees north (a line between Lost Angeles and Columbia, South Carolina) your body can make vitamin D from sun exposure yearlong. However, it’s important to expose a large portion of bare skin (like your midriff) to mid-day sun for at least 15 minutes every day. Most people are unable to fit this into their schedule, so vitamin D supplementation is highly recommended, especially since so few foods contain it.

According to Michael Holick, PhD, MD, an internationally recognized expert on vitamin D and director of the Vitamin D, Skin and Bone Research Laboratory at Boston University Medical Center, approximately one billion people throughout the world are deficient in vitamin D.

Blacks, Browns, and other dark skinned individuals are at even higher risk for inadequate levels of vitamin D because their skin isn’t able to absorb as much sunlight. This may be one of the reasons that these populations have fared so poorly in the fight against COVID-19.

Foods that are high in vitamin D

  • Cod liver oil, salmon, tuna, sardines, herring, smoked whitefish, rainbow trout, swordfish
  • Milk and fortified non-dairy drinks (orange juice, coconut, soy, almond, etc.)
  • Fortified cereals
  • Mushrooms are the only food in the produce section that has vitamin D. Portobello, maitake, white button have the highest vitamin D content.

How much should you take?

Dr. Holick says, “I recommend to all of my patients that they should take 2000-3000 IU of vitamin D a day from dietary sources, sensible sun exposure and supplements. I believe that it is important for women to take at least 2000 IU of vitamin D a day. Although many of the studies are association studies there continues to be strong evidence that increasing vitamin D intake has other health benefits besides those for bone health. From my perspective there is no downside to increasing your vitamin D intake to levels I have recommended in “The Vitamin D Solution” which is 1000 IU of vitamin D a day for children and 2000-3000 IU of vitamin D for adults.” https://www.nejm.org/doi/full/10.1056/nejmra070553

If you’re over 60, consider taking at least 3,000 IU daily during the summer, and take 5,000 IU in the winter if you want to increase your protection against COVIC-19 and other respiratory illnesses.

Zinc

Zinc is naturally found in the body and is the second most abundant trace element. It is commonly taken to relieve symptoms of the common cold and influenza. It prevents viral replication and the binding of viruses to cells. However, moderate deficiencies can increase the risk of infection.

How does it help?

Researchers are working on lab studies showing how zinc supplementation can help reduce risk of COVID-19. But we know this: Zinc is thoroughly involved in cell-mediated immunity against any infectious agent such as bacteria and virus. Zinc is one of the major factors that control function and proliferation of neutrophils, natural killer (NK) cells, macrophages, and T and B lymphocytes as well as cytokine production by the immune cells. Zinc also mediates protection from the adverse effect of ROS that are generally produced during inflammatory processes. 

Zinc supplementation might play an important role to COVID-19 patients by adding immune boosting effects with anti-viral drugs.

Foods that are high in zinc

  • Meat
  • Shellfish
  • Legumes—chickpeas, lentils, beans
  • Seeds—pumpkin
  • Nuts —cashews,almonds, pinenuts, peanuts
  • Dairy
  • Eggs

How much should you take?

The recommended daily allowance of zinc will vary according to the age, sex, and health conditions of an individual. For healthy adults, the recommended daily allowance is typically 15–30 mg of elemental zinc. Make sure the supplement contains some copper, which makes the zinc more absorbable. The supplement should contain a ratio of 15 mg of zinc to 1 mg of copper.

Other important supplements

Vitamin C and selenium are antioxidants with lots of studies showing how they help support the immune system.

Selenium

Selenium is an essential trace element obtained from the diet (i.e. fish, meat and cereals) which has been found to affect the severity of a number of viral diseases in animals and humans.

Margaret Rayman, Professor of Nutritional Medicine at the University of Surrey, said: “Given the history of viral infections associated with selenium deficiency, we wondered whether the appearance of COVID-19 in China could possibly be linked to the belt of selenium deficiency that runs from the north-east to the south-west of the country.”

Examining data from provinces and municipalities with more than 200 cases and cities with more than 40 cases, researchers found that areas with high levels of selenium were more likely to recover from the virus. For example, in the city of Enshi in Hubei Province, which has the highest selenium intake in China, the cure rate (percentage of COVID-19 patients declared ‘cured’) was almost three-times higher than the average for all the other cities in Hubei Province. By contrast, in Heilongjiang Province, where selenium intake is among the lowest in the world, the death rate from COVID-19 was almost five-times as high as the average of all the other provinces outside of Hubei.

Most convincingly, the researchers found that the COVID-19 cure rate was significantly associated with selenium status, as measured by the amount of selenium in hair, in 17 cities outside of Hubei. http://www.sciencedaily.com/releases/2020/04/200429105907.htm

How does it help?

Selenium supplementation modulates the inflammatory response in acute respiratory distress syndrome (ARDS) patients by restoring the antioxidant capacity of the lungs, thus improving lung function. When there isn’t enough antioxidant capacity in the lungs because of selenium deficiency, mutations within viruses occur. This makes them even more dangerous and infectious.

Foods that are high in selenium

  • Brazil nuts
  • Tuna
  • Shellfish–oysters
  • Pork chops
  • Beef
  • Chicken
  • Firm Tofu
  • Whole wheat pasta, kamut, oatmeal, brown rice
  • Shrimp
  • Shitake mushrooms

How much should you take?

It’s best to make sure you’re eating foods containing selenium. When taken by mouth: Selenium is LIKELY SAFE for most people when taken by mouth in doses less than 400 mcg daily, short-term. However, selenium is POSSIBLY UNSAFE when taken by mouth in high doses or for a long time. Taking doses above 400 mcg can increase the risk of developing selenium toxicity. Most multi-vitamins contain selenium. Check yours (and yes, you shuld be taking a multi-vitamin. Make sure it contains adequate selenium. The recommended Daily Value (DV) or daily allowance for selenium is 55 mcg per day for adults. During pregnancy, a woman should get 60 mcg, and lactating women should get 70 mcg a day.

Look for my next blog in which I’ll discuss how vitamin C infusions can help keep you from being put on a ventilator if you get COVID-19.


 

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Barbra Cohn cared for her husband Morris for 10 years. He passed away from younger-onset Alzheimer’s disease in 2010. Afterward, she was compelled to write “Calmer Waters: The Caregiver’s Journey Through Alzheimer’s & Dementia”—Winner of the 2018 Book Excellence Award in Self-Help—in order to help other caregivers feel healthier and happier, have more energy, sleep better, feel more confident, deal with feelings of guilt and grief, and to ultimately experience inner peace. “Calmer Waters” is available at AmazonBarnes & NobleBoulder Book StoreTattered Cover Book Store,  Indie Bound.org, and many other fine independent bookstores, as well as public libraries.

14 Ways to boost your immune system to stave off the VIRUS.

boost your immune systemDear Readers,

This is a crazy time, and there’s a lot of misinformation out there.

I’d like to share time-tested information, and a few new tips I’ve learned from health professionals about ways to boost your immunity . . . and the immunity of the people you lovingly care for.

You’ve heard it a million times: wash your hands, don’t touch your face, stay hydrated and rested, and eat well.

What else should you do?

The mucous membranes—the linings of our nose, throat, sinuses, eustachian tubes, upper respiratory system—-are the body’s first defense against bacteria, viruses and other toxins. Mucous traps the stuff we don’t want inside of us. We sneeze and cough in order to rid ourselves of the “invaders.” We also swallow the invaders. If the good bacteria in our stomach is doing its job, stomach acid will destroy the invaders.  So, you want to keep your mucous membranes hydrated. It’s important they stay moist and lubricated.

  1. Turn on the humidifier if you live in a dry climate. If you don’t have one, consider buying one.
  2. Use a Netti pot or Neil Med sinus rinse with Alkalol, an antimicrobial nasal wash. And please use distilled water, not purified water. This helps clear mucous to support healthier nasal passages.
  3. If your sinuses are congested use an ayurvedic oil in your nostril. Sinus Care & Nasal Oils. You can also use a cooking oil such as sesame, olive, or coconut. Just put a couple of drops of oil in each nostril 3 times a day.
  4. Gargle twice a day with warm salt water or oil. There is an email going around that says it will eliminate the virus. Although I don’t have a scientific reference for this, it’s worth a try.  Oil Pulling is an ayurvedic practice of holding and swishing 1-2 teaspoonfuls of herbalized oil in your mouth for 5-10 minutes. This practice is also said to reduce infection from bacteria and viruses.
  5. Drink water. Lots of it. Forget about sodas and juices. You need to stay hydrated in order to flush the toxins out of your body, and that includes the virus. Herbal tea and coconut water are good, also. Have coconut water on hand just in case you get a fever. It provides electrolytes naturally, without getting artificial color or sugars found in Gatorade.
  6. Take Vitamin D3–2-5,000 IU a day, depending on health and body weight. Please read my article Are You Getting Enough Vitamin D? Most people are not getting enough and that puts us in greater risk for getting the flu, and now COVID-19.
  7. Did you know that 70% of your immune system lies in your gut? Probiotics are live bacterial microorganisms that populate the human gastrointestinal tract. They combat the daily bombardment of toxins and pathogens (bacteria, fungus, parasites, and viruses) that enter our digestive system every day through contaminated food and other toxins. Recent studies show that the bacteria in your gut can also affect your mental health, mood and stress levels. Fermented foods such as kombucha, Greek yogurt, kefir, sauerkraut, miso, cottage cheese are probiotics. Probiotic bacteria colonize the digestive tract with good bacteria. Prebiotics are the food and nutrients that feed probiotics. Prebiotic fiber is found in fruits and vegetables such as artichokes, jicama, wild yams, onions and garlic, asparagus, beans, oats, chicory root and Jerusalem artichokes. Prebiotics support mineral absorption, vitamin utilization, and healthy blood sugar levels. Your gut needs both pro- and prebiotics in order to stay healthy and keep you healthy.
  8. Include EFAs (Essential Fatty Acids) in your diet. EPA/DHA from fish, nuts or algae are essential for our brain, nerves and immune system to work efficiently. Under stress, our systems become inflamed so it’s more important now than ever to make sure you’re getting enough. Ways to increase your DHA intake: eat cold-water fish such as wild-caught salmon, sardines and mackerel, at least twice a week. Add flax meal to cereal and baked goods, sprinkle flax oil on your salad, eat a small handful of walnuts at least several times a week.
  9. Take a Multivitamin Mineral for overall added protection. Make sure it is high quality.
  10. Zinc has been shown to inhibit various coronaviruses in a couple of studies. SARS coronavirus, and ZN (2+) inhibits coronavirus.  However, it hasn’t been tested on COVID-19. Still, it is always a good idea to make sure you are taking a zinc supplement, and that doesn’t mean the zinc lozenge. Most people are deficient in zinc. A researcher at the University of Pittsburgh recommends taking 25 mg of zinc morning and evening.
  11. Make sure you’re getting enough Vitamin A. Beta Carotene is the antioxidant of choice for people who are unsure about which vitamin A to take. It is the precursor of vitamin A and can be converted into vitamin A if the body needs it. It gives added protection to the immune system, skin, eyes, and lungs.
  12. Get plenty of Vitamin C-Your body does not manufacture vitamin C on its own, nor does it store it. Since vitamin C is water-soluble, it dissolves in water, and leftover amounts of the vitamin leave your body through urine. That means you need to maintain your vitamin C intake by eating citrus and other fruits and vegetables that are high in vitamin C. Dr. Ed Bauman, founder and president of Bauman College of Nutrition recommends taking a high-quality vitamin C supplement such as Vitamin C with Bioflavonoids: 500 mg. 3-5 x day of Amla (natural vitamin C with bioflavonoids from gooseberry) or 2-4 times that amount of buffered vitamin C from ascorbic acid. Or, take Ascorbyl palmitate. It is a fat-soluble form of vitamin C, which is better absorbed than ascorbic acid, the water-soluble form. It offers all the benefits of ascorbic acid, plus it won’t flush out of the body as quickly as ascorbic acid, and it is able to be stored in cell membranes until the body needs it.
  13. Eat a variety of colored fruits and vegetables. There’s not much left on the grocery store shelves at the moment. But the next time you shop, fill up your cart with fruits and veggies that contain antioxidants and carotenoids to boost your immune system.
  14. Make Healthy Choices

Choose these

  • Water, green tea, herbal teas
  • Nuts & seeds
  • Avocado, olive oil, omega-3 fatty acids
  • Fresh fruits and Veggies
  • Fish, high-quality protein
  • SOUL foods (seasonal, organic, unadulterated, local)
  • Sugar alternatives: stevia, monk fruit, coconut sugar, maple syrup, agave, birch sugar, honey

Avoid these

  • Coffee, soda, artificial sweeteners
  • Chips, cookies, pastries, candy
  • Poor quality fats (hydrogenated,
  • Processed lunch meats
  • Dairy products with rBGH (growth hormones)

Remember this

Whether you’re eating breakfast, lunch, dinner or a snack, always think protein! Protein helps build cells and tissues and supports our strength.

Build your meal around chicken, fish, tofu, cottage cheese or eggs, and then add low-starch vegetables or fruits. The general rule is to eat 3-4 ounces of lean, dense meat or 6 ounces of fish. Women should aim for around 30 grams of protein. Men should aim for around 40 grams of protein. Another rule of thumb is to divide your plate in half. Fill half of the plate with veggies, one quart with a protein, and the other quarter with a whole grain such as quinoa, rice, barley, etc.

Please take care of yourself. And if you are a caregiver, take double care of yourself. You won’t be of help, if you get sick.

All the best to you and your family.

Barbra


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Barbra Cohn cared for her husband Morris for 10 years. He passed away from younger-onset Alzheimer’s disease in 2010. Afterward, she was compelled to write “Calmer Waters: The Caregiver’s Journey Through Alzheimer’s & Dementia”—Winner of the 2018 Book Excellence Award in Self-Help—in order to help other caregivers feel healthier and happier, have more energy, sleep better, feel more confident, deal with feelings of guilt and grief, and to ultimately experience inner peace. “Calmer Waters” is available at AmazonBarnes & NobleBoulder Book StoreTattered Cover Book Store,  Indie Bound.org, and many other fine independent bookstores, as well as public libraries.

Do you have any of these risk factors for Alzheimers?

Woman with hypertension treating by a nurse

  1. Dizziness when standing up
  2. Reduced levels of plasmalogens
  3. High blood pressure
  4. Obesity
  5. Alcohol
  6. Head trauma
  7. Family history
  8. Smoking
  9. Age
  10. Social Isolation (see Loneliness vs. Aloneness: Why one is dangerous to your health

Most people know that old age is a risk factor for Alzheimer’s disease. In fact, after age 65 the risk of Alzheimer’s doubles every five years. And after age 85 one out of three seniors dies with Alzheimer’s or other form of dementia. You’ve probably also heard that obesity, alcohol consumption, head trauma, family history, smoking, and social isolation put you at increase risk.

But here are a few risk factors that you may not have heard about.

Dizziness when standing up

A new risk factor, and a concern for me personally, is orthostatic hypotension (OH), a fancy name for feeling  dizzy when you stand up. According to a new study, middle-aged people who experience orthostatic hypotension may have a higher risk of developing dementia later in life. The study analyzed data from 11,709 participants without a history of coronary heart disease or stroke. It concluded that individuals who experience a drop in systolic blood pressure (the bottom number) of at least 20 mm Hg or a drop in diastolic blood pressure (the top number) of at least 10 mm Hg on standing are said to have orthostatic hypotension.

Over a 25-year period, 1,068 participants developed dementia and 842 had an ischemic stroke. Compared to persons without OH at baseline, those with OH had a higher risk of dementia and ischemic stroke. Persons with OH had greater, although insignificant, cognitive decline over 20 years. But since the study doesn’t take any other risk factors into consideration, I’m not going to lose sleep over this.

2. We’ve heard how omega 3 fatty acids are necessary for a healthy cardiovascular system. But if your liver doesn’t process these key lipids properly it can spell trouble in your brain.

Reduced levels of plasmalogens — a class of lipids created in the liver that are integral to cell membranes in the brain — are associated with an increased risk of Alzheimer’s Disease, according to new research presented at the Alzheimer’s Association International Conference (AAIC) 2018 by Mitchel A. Kling, MD, an associate professor of Psychiatry in the Perelman School of Medicine at the University of Pennsylvania and the Veterans Affairs Medical Center. A reduced level is also implicated in Down’s Syndrome and Parkinson’s disease.

In 2012, scientists found a 40% reduction in plasmalogen content of white matter in the brain in individuals with early stage Alzheimer’s.

Plasmalogens are created in the liver and are dispersed through the blood stream in the form of lipoproteins, which also transport cholesterol and other lipids to and from cells and tissues throughout the body, including the brain. The researchers measured several plasmalogens including those containing omega-3 fatty acids docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), as well as an omega-6 fatty acid and closely-related non-plasmalogen lipids, in blood-based fluids collected from two groups. The first group included 1,547 subjects that have Alzheimer’s disease, MCI or significant memory concerns (SMC), and subjects who were cognitively normal (CN) and who are enrolled in the Alzheimer’s Disease Neuroimaging Initiative. The second group included 112 subjects from the Penn Memory Center, including those with Alzheimer’s, MCI, and CN.

“Our findings provide renewed hope for the creation of new treatment and prevention approaches for Alzheimer’s disease,” Kling said. “Moving forward, we’re examining the connections between plasmalogens, other lipids, and cognition, in addition to gene expression in the liver and the brain. While we’re in the early stages of discovering how the liver, lipids, and diet are related to Alzheimer’s disease and neurodegeneration, it’s been promising.”



You would think that taking omega 3s would help, right? Well, according to the study, they don’t. However, plasmalogens from mussels are being sold in Japan and Singapore as a health supplement for Alzheimer’s disease. See Scallop-derived PLASMALOGEN. There is also a Singapore product for sale in the U.S. that supposedly helps your body increase the level of plasmalogens. It’s called NeuroREGAIN. You can read about it here: NeuroREGAIN

According to the first study cited, these products don’t help because of the pH in the
digestive system and the ability to utilize the ingredients.
But it’s up to you. I tried lots of things with my husband, and if he were still alive I’d probably try this product, too.


3. Recently, researchers from the Rush Alzheimer’s Disease Center at Rush University Medical Center in Chicago, IL, set up a study funded by the National Institutes of Health to look for links between blood pressure and physical markers of brain health in older adults. The findings are published in the July 11, 2018, online issue of Neurology. Study co-author Dr. Zoe Arvanitakis explains the types of pathology they were searching for.

“We researched whether blood pressure in later life was associated with signs of brain aging that include plaques and tangles linked to Alzheimer’s disease, and brain lesions called infarcts, areas of dead tissue caused by a blockage of the blood supply, which can increase with age, often go undetected and can lead to stroke, said Arvanitakis.”

Healthy blood pressure is less than 120/80 millimeters of mercury (mmHg). The higher number is called systolic blood pressure, the pressure in the blood vessels when the heart beats. The lower number is called diastolic blood pressure, the pressure when the heart is at rest.

For the study, 1,288 older people were followed until they died, which was an average of eight years later. The average age at death was 89 years. Blood pressure was documented yearly for each participant and autopsies were conducted on their brains after death. The average systolic blood pressure for those enrolled in the study was 134 mmHg and the average diastolic blood pressure was 71 mmHg. Two-thirds of the participants had a history of high blood pressure, and 87 percent were taking high blood pressure medication. A total of 48 percent of the participants had one or more brain infarct lesions.

Researchers found that the risk of brain lesions was higher in people with higher average systolic blood pressure across the years. For a person with one standard deviation above the average systolic blood pressure, for example 147 mmHg versus 134 mmHg, there was a 46 percent increased risk of having one or more brain lesions, specifically infarcts. For comparison, the effect of an increase by one standard deviation on the risk of having one or more brain infarcts was the equivalent of nine years of brain aging.

Those with one standard deviation above the average systolic blood pressure also had a 46 percent greater chance of having large lesions and a 36 percent greater risk of very small lesions. Arvanitakis noted that an important additional result of the study was that people with a declining systolic blood pressure also had an increased risk of one or more brain lesions, so it was not just the level but also the declining blood pressure which was associated with brain lesions.

Separately, higher average diastolic blood pressure was also related to brain infarct lesions. People who had an increase of one standard deviation from an average diastolic blood pressure, for example from 71 mmHg to 79 mmHg, had a 28 percent greater risk of one or more brain lesions.

The results did not change when researchers controlled for other factors that could affect the risk of brain lesions, such as whether they used high blood pressure drugs.

When looking for signs of Alzheimer’s disease in the brain at autopsy, researchers found a link between higher average late-life systolic blood pressure across the years before death and a higher number of tangles, but not plaques. Arvanitakis said this link is difficult to interpret and will need more research.

 The bottom line is be aware of your blood pressure and how to maintain healthy levels.

Natural remedies to support healthy blood pressure and circulation:

  • Magnesium
  • Potassium
  • Vitamin B complex
  • Vitamin C
  • CoQ10
  • Resveratrol
  • Astaxanthin
  • Nattokinase
  • Pomegranate
  • Acetyl-L-carnitine

A healthy heart supports a healthy brain. Here are 12 ways to support both.

12 ways to support a healthy heart

  1. Eat a nutritious, high-fiber, low-fat heart healthy diet.
  2. Include foods high in phytonutrients (the nutrients found in plants)
  3. Get plenty of foods containing omega-3 fatty acids (found in cold water fish). Vegetarians should take flax-seed oil or ground flax seed.
  4. Take nutritional supplements proven to support a healthy heart
  5. Practice a stress reduction technique such as yoga or meditation
  6. Exercise
  7. Stop smoking!
  8. Reduce and/or avoid alcohol
  9. Get an annual physical exam to rule out other health factor risks
  10. Protect yourself from environmental toxins
  11. Drink 6 to 8 glasses of purified, filtered water every day
  12. Get plenty of restful sleep!

 

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Barbra Cohn cared for her husband Morris for 10 years. He passed away from younger-onset Alzheimer’s disease in 2010. Afterward, she was compelled to write “Calmer Waters: The Caregiver’s Journey Through Alzheimer’s & Dementia”—Winner of the 2018 Book Excellence Award in Self-Helpin order to help other caregivers feel healthier and happier, have more energy, sleep better, feel more confident, deal with feelings of guilt and grief, and to ultimately experience inner peace. “Calmer Waters” is available at AmazonBarnes & NobleBoulder Book StoreTattered Cover Book Store,  Indie Bound.org, and many other fine independent bookstores, as well as public libraries.

A UTI, fall or a cold can lead to cognitive decline and even death in a person with Alzheimer’s disease

Dementia disease and a loss of brain function and memories

November is Alzheimer’s Awareness Month 

People with Alzheimer’s who get even a mild respiratory or gastrointestinal infection, or a bump or bruise are at risk for having a significant, permanent memory loss, according to a report that was published in the September 8, 2009 issue of the journal Neurology. These patients can have high levels of tumor necrosis factor—alpha (TNF-a)—a protein that is linked to inflammation and is associated with memory loss and cognitive decline.

In the study, which was done at the Clinical Neurosciences Research Division at the University of Southampton, United Kingdom, 222 Alzheimer’s patients were followed for six months. Of those, 110 people had an infection or injury that resulted in inflammation. These individuals had twice the memory loss during that period of time as the individuals who did not have an illness or injury. Researchers attribute the memory loss to inflammation. In patients whose TNF-a levels were high to begin with, an infection increased their memory loss to 10 times more than those who had low TNF-a levels.

Clive Holmes, PhD, lead researcher, said that this population should be vaccinated against the flu, and infections and injuries should be treated as soon as possible.

It is not uncommon for an elderly person to die from a urinary tract infection, especially someone who has dementia. Even a mild cold can develop into a serious pneumonia and lead to death in an elderly person. My husband developed a kidney stone, and died six weeks later. He progressed from a person in mid- to late-stage Alzheimer’s to someone in the final stage of Alzheimer’s, unable to walk or talk.

Tips for keeping you and your loved one healthy and safe

  • Inoculate against flu, pneumonia and shingles
  • Boost immunity with zinc, vitamin D and vitamin C
  • Prevent falls and accidents (recommended: Complete Guide to Alzheimer’s Proofing Your Home by Mark L. Warner
  • Reduce systemic inflammation with a curcumin (turmeric extract) supplement
  • Use a humidifier to moisturize nasal passages and mucous membranes to help keep them healthy
  • Engage in gentle exercise to reduce inflammation
  • Keep hydrated by drinking at least 6-8 glasses of water each day
  • Reduce risk of urinary tract infections with D-Mannose powder and cranberry extract 
  • Use essential oils (lemon, peppermint, lavender, frankincense, bergamot, thyme, sandalwood, vetiver, myrrh) to boost immunity. For more information about the use of aromatherapy to reduce stress, improve immunity, reduce agitation, and to promote relaxation read chapter 18 “Aromatherapy” in “Calmer Waters: The Caregiver’s Journey Through Alzheimer’s & Dementia” by Barbra Cohn
  • Eat yogurt. 70% of your immune system lies in your gut. Probiotics are live bacterial microorganisms that populate the human gastrointestinal tract. They combat the daily bombardment of toxins and pathogens (bacteria, fungus, parasites, and viruses) that enter our digestive system every day through contaminated food and other toxins. Recent studies show that the bacteria in your gut can also affect your mental health, mood and stress levels. Fermented foods such as kombucha, Greek yogurt, kefir, sauerkraut, miso, cottage cheese are probiotics. Probiotic bacteria colonize the digestive tract with good bacteria. Prebiotics are the food and nutrients that feed probiotics. Prebiotic fiber is found in fruits and vegetables such as artichokes, jicama, wild yams, onions and garlic, asparagus, beans, oats, chicory root and Jerusalem artichokes. Prebiotics support mineral absorption, vitamin utilization, and healthy blood sugar levels. Your gut needs both pro- and prebiotics in order to stay healthy and keep you healthy.
  • Drink mineral broth. It helps alkalinize the body and warm the system. It also helps counter the negative effects of stress. Have it as a bowl of soup or sip it throughout the day. Use your vegetables scraps or chop 2 cups yams, 1 medium potato, 1 cup zucchini, 1 cup cabbage, 1 cup green beans, 2 cups celery, 1 cup onions. Add herbs, garlic, parsley–anything you like. Place in a large pot, cover with water, bring to a boil, turn down to a simmer, and cover for 3-5 hours. For more information read chapter  31 “Nutrition” in “Calmer Waters: The Caregiver’s Journey Through Alzheimer’s & Dementia” by Barbra Cohn

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